Gas Chromatography in Metabolomics Study

Integrated Transcriptomics and Metabolomics Study of Retinoblastoma Using Agilent Microarrays and LC/MS/GC/MS Platforms

Vinegar Metabolomics: An Explorative Study of Commercial Balsamic Vinegars Using Gas Chromatography-Mass Spectrometry

Balsamic vinegar is a popular food condiment produced from cooked grape must by two successive fermentation (anaerobic and aerobic) processes. Although many studies have been performed to determine the composition of major metabolites, including sugars and aroma compounds, no study has been undertaken yet to characterize the comprehensive metabolite composition of balsamic vinegars. Here, we pr...

Separation Technique for the Determination of Highly Polar Metabolites in Biological Samples

Metabolomics is a new approach that is based on the systematic study of the full complement of metabolites in a biological sample. Metabolomics has the potential to fundamentally change clinical chemistry and, by extension, the fields of nutrition, toxicology, and medicine. However, it can be difficult to separate highly polar compounds. Mass spectrometry (MS), in combination with capillary ele...

Agilent Metabolomics Workflow Solutions Using LC/MS, GC/MS, and NMR

Agilent Technologies is an established leader in providing metabolomics solutions. Metabolomics refers to the identification and quantitation of metabolites, which are the small organic molecules that are used in biological processes within cells. These molecules are important indicators of biological function, and their study can provide unique insights into cell physiology, metabolism, and to...

Mass spectrometry-based metabolomics

untargeted. Targeted metabolomics focuses on a subset of metabolites involved in one or more pathways; the chemical identities of metabolites to be measured are known, authentic standards are available in these studies. The goal of untargeted metabolomics is to observe global metabolite profiling differences between sample types, experiments are designed to maximise the coverage of metabolites....